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Innovations in Supercritical Fluids
Uses of SCF
Applied Separations is leading the charge, discovering innovative ways to use Supercritical Fluids (SCF) in many industries. With our R&D team, in-house engineers, and visionary approach, we've helped companies all over the world make the switch to SCF.

Why try SCF? That's simple!
- Improve processes
- Save money
- Go "green"
Supercritical Fluids leave no residue or hazardous waste, making them the perfect solvent for many processes.
Supercritical Fluids are not new. They were discovered in 1822 by Baron Charles Cagniard de la Tour, and have been used regularly in laboratories for thirty years. With today's push toward Green Chemistry and Nanotechnology, supercritical fluids have become more widely used in applications you might not expect.
The uses of Supercritical Fluids that we have proven so far are listed below. Remember, these are just some of the ways SCF can be used to improve processes and "go green" in business. Contact us and we'll work with you to develop a Supercritical Fluid application for your needs.
Applied Separations offers a full line of SFE systems to meet the needs in your laboratory.
Spe-ed SFE Prime
Applied Separations has created the first teaching tool for Supercritical Fluids. Safe and affordable, this instrument is perfect for the classroom.
Supercritical Fluids (SCF) Education
As thought-leaders in the world of Supercritical Fluids, Applied Separations strikes to share its knowledge and experience to further the use of Supercricial Fluids.
Laboratory Instruments
Applied Separations has the instruments you need in your laboratory to handle the most complex to the most straight-forward SCF projects.
Pilot Plants: Small Production
The basic supercritical pilot plant is a "no frills" caster-mounted system for the budgetminded. You, as the user, determine the size of the system...
Industrial Scale Production
Applied Separations will work with you to pin-point your needs and determine the feasibility of your project.
Metal Injection Molding
Supercritical Fluids will revolutionize the debinding process.
Accessories
Not only do we offer SCF instruments, but a full line of accessories the customize your SCF instruments are also available.
Applications
We have compiled a comprehensive list of SCF applications available for free. Click here to view the list of the SCF applications you can put to use immediately in your lab.
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Let Green-I-Am introduce you to the world of SCF!
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What is SCF?
Carbon dioxide is in its supercritical fluid state when both the temperature and pressure equal or exceed the critical point of 31°C and 73 atm (see diagram). In its supercritical state, CO2 has both gas-like and liquid-like qualities, and it is this dual characteristic of supercritical fluids that provides the ideal conditions for extracting compounds with a high degree of recovery in a short period of time.
By controlling or regulating pressure and temperature, the density, or solvent strength, of supercritical fluids can be altered to simulate organic solvents ranging from chloroform to methylene chloride to hexane. This dissolving power can be applied to purify, extract, fractionate, infuse, and recrystallize a wide array of materials. Because CO2 is non-polar, a polar organic co-solvent (or modifier) can be added to the supercritical fluid for processing polar compounds. By controlling the level of pressure/ temperature/ modifier, supercritical CO2 can dissolve a broad range of compounds, both polar and non-polar.

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