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ASI at Pittcon 2007
Extractions! Extractions! Extractions!
58th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy
February 25 - March 2, 2007
McCormick Place, Chicago, IL
Best Cartridge Artist! |
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At the booth this year, we had a contest for the best "Cartridge Art" creations. We are happy to announce that the winner was Mali Marvin, a Senior Chemist from Rockville, TN. She is now the proud owner of the Best Cartridge Artist title and a brand new iPod.
Thanks for all the entries! |
In addition to the art created at the show, we had a local Allentown, PA art class compete for a gift certificate and bragging rights. Check out the story and creations.
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Poster Presentations
Please contact us for more information on any of the presentations and papers listed below.
Poster Presentation: Monday afternoon, 2/26 |
| Session: |
AGRICULTURE |
| Title:: |
(770-5 P) The Supercritical Fluid Extraction of Antibiotic and Pesticide Residues from Eggs |
| Presenters:: |
Al Kaziunas, Rolf Schlake |
| Abstract:: |
Public concern about pesticide and antibiotic trace residues in the food supply is increasing. The exposure of laying hens to antibiotic products in feed results in trace amounts of antibiotics and antibiotic metabolites in their eggs. In addition, pesticide residues can be concentrated in the egg supply contributing to potentially dangerous human exposure. This paper describes the extraction of eggs with supercritical carbon dioxide for chloraphenicol, sulfamethazine, and organochlorine pesticids. Residues at the ppm and ppb level are extracted with supercritical CO2 and cleaned up with solid phase extraction cartridges. The improved methods detailed in this paper reduce extraction time, solvent consumption and cleanup steps in the analysis of trace residues when compared to traditional extraction techniques. |
Poster Presentation: Monday afternoon, 2/26 |
| Session:: |
HOMELAND SECURITY/FORENSICS
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| Title:: |
(820-3 P) The Rapid Automated Pressurized Solvent Extraction of Chemical Warfare Agents from Soil Samples |
| Author:: |
Al Kaziunas, Rolf Schlake |
| Abstract:: |
The rapid extraction of chemical warfare agent surrogate compounds from soil samples was conducted using an automated pressurized solvent extraction instrument. Organophosphorus pesticides were used as surrogate compounds for nerve agents and extracted from soil samples to evaluate the pressurized parallel solvent extraction technology for this application. The results were compared to traditional solvent extraction techniques for recovery and reproducibility. In addition, the ability to extract and process high volume sample loads rapidly was evaluated in a working environmental laboratory using the extraction of PCBs from soil as a test model. Data is presented detailing the procedures, manpower and equipment required to extract 200 soil samples in one day for chemical warfare agents. |
Poster Presentation: Monday afternoon, 2/26 |
| Session:: |
HOMELAND SECURITY/FORENSICS |
| Title:: |
Using Supercritical Fluids to Evaluate Human Exposure to Chemical Agents |
| Author:: |
Rolf Schlake, Al Kaziunas |
| Abstract:: |
Human exposure to chemical agents requires non-invasive and non-hazardous methods to sample and quantitatively determine exposure levels. Supercritical fluid extraction has been successfully used in the extraction of organophosphorus compounds from lipid matrices using carbon dioxide. The application of this technique in the evaluation of nerve agent exposure of the population involves using a harmless lipid matrix to contact the surface of skin with the subsequent supercritical fluid extraction of organophosphorus compounds from the lipid matrix. A scheme detailing the procedure is described together with recovery data using organophosphorus pesticides as surrogate compounds. Cleanup steps can be minimized by judicious selection of extraction conditions and the use of binary gases. |
Poster Presentation: Tuesday morning, 2/27 |
| Session:: |
FOOD SCIENCE I: EVALUATION AND SAFETY |
| Title:: |
(1120-12 P) The High Throughput Pressurized Solvent Extraction of Pesticide Residue from Foods |
| Author:: |
Al Kaziunas, Rolf Schlake |
| Abstract:: |
The traditional methods used to prepare food samples for pesticide residue analysis consume large quantities of solvents and large amounts of laboratory time in the sample work up process. This paper describes the application of pressurized solvents in the simultaneous extraction of (6) six samples for the analysis of organochlorine pesticide residues. The results are compared to the traditional solvent extraction technique. Many different food matrices (vegetable and grains) are analyzed and the preparation steps for the successful processing of food samples are detailed. In addition, the procedures, equipment and manpower required to process a large number of samples in an eight hour operating day are described. |
Poster Presentation: Tuesday afternoon, 2/27 |
| Session: |
ANALYTICAL TECHNIQUES FOR DRUG DISCOVERY |
| Title: |
(1390-9 P) Supercritical Fluid Extraction of Pharmaceutical Compounds from Natural Products |
| Author: |
Rolf Schlake, Al Kaziunas |
| Abstract:: |
Natural products contain many unique compounds of pharmaceutical interest. The extraction of these compounds when screening for pharmaceutical activity is typically conducted using organic solvents. Supercritical carbon dioxide offers an alternative methodology for the extraction of pharmaceutically active compounds. All samples were extracted on a bench top supercritical fluid extractor capable of 4 simultaneous extractions. The density of the supercritical fluid was systematically manipulated to produce a broad range of fractions. In addition, the non polar character of supercritical CO2 was modified to sequentially produce fractions of polar compounds. The extraction of pharmaceutical compounds including antimalarials, antimicrobials, and antioxidants from wood, leaves, roots, and flowers is described. |
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Want to know more?
If you would like more information about our upcoming or past events, or if you would like to have Applied Separations attend your event, please contact us. |
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